RCOG GTG 69

PUQE-24

Nausea & vomiting severity (last 24 h)

Clinician mode

Low risk

3

Mild NVP

  • Ladder: cyclizine/promethazine → prochlorperazine/metoclopramide → ondansetron (>10/40 preferred) → steroids.
  • PUQE ≥13, ketonuria, weight loss ≥5% → admit for IV fluids + thiamine.
  • Always give thiamine before any glucose-containing fluid (Wernicke prevention).

Reference range

Mild ≤6 · Moderate 7–12 · Severe ≥13 (validated PUQE-24)

Common pitfalls

  • Only counts symptoms in the last 24 h.
  • Score can miss dehydration — always check ketonuria & weight.

For educational use only

Not medical advice. Verify dosing against the BNF and your local trust guidelines before prescribing.