Second-lineBricanyl

Terbutaline

β2-adrenergic agonist

Acute tocolysis for intrauterine resuscitation.

SCIV

First-line for

  • Hyperstimulation with fetal compromise
  • Intrauterine resus during CTG abnormality / ECV

Mechanism

β2 stimulation → ↑ cAMP in myometrium → uterine relaxation.

Terbutaline

  • Relax the womb — short window only

Dosing

Tocolysis
250 micrograms SC (or slow IV) — single dose

Contraindications

  • AbsoluteMaternal cardiac disease, severe pre-eclampsia, APH
  • CautionDiabetes (hyperglycaemia), thyrotoxicosis

Side effects

  • Tachycardia, tremor, palpitations
  • Pulmonary oedema (esp. with steroids/fluid)
  • Hyperglycaemia, hypokalaemia

Fetal & maternal notes

  • Neonatal hypoglycaemia.
  • Not for prolonged tocolysis (cardiac death — FDA warning).

Key interactions

  • Steroids + fluids

    Avoid

    Pulmonary oedema

  • β-blockers

    Caution

    Antagonism

Clinical pearls

  • 💡 Used while preparing for cat-1 LSCS.
  • 💡 Avoid >48 h.

Content last reviewed: REPLACE_ME (e.g. 2026-07)

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For educational use only

Not medical advice. Verify dosing against the BNF and your local trust guidelines before prescribing.