AlternativeMenopur
Human menopausal gonadotropin (hMG)
Gonadotropin — urinary FSH + LH activity
Combined FSH/LH stimulation — hypogonadotropic hypogonadism.
SC / IM
First-line for
- Hypogonadotropic hypogonadism ovulation induction
- IVF (some protocols)
Mechanism
Extracted FSH + LH activity → follicular growth with concurrent luteinisation support.
"hMG when LH is missing"
- Central hypogonadism
- Watch OHSS
- Trigger with hCG
Dosing
- Start
- 75–150 IU daily SC/IM, titrate by response
Contraindications
- AbsoluteAs per recombinant FSH
Side effects
- OHSS
- Multiple pregnancy
- Injection reaction
Fetal & maternal notes
- • Stop at conception
Key interactions
Recombinant FSH
CautionAdditive stimulation
Clinical pearls
- 💡 Kallmann syndrome — hMG needed as LH activity absent
- 💡 Monitor oestradiol closely
Content last reviewed: REPLACE_ME (e.g. 2026-07)
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